The news reporters obtained a quote from the research from Instituto de Salud Carlos III, "Here we measure the spectrum of bond strengths and flexibilities in antibody-antigen interactions using optical tweezers. We characterize the mechanical evolution of polyclonal antibodies generated under infection and the ability of a monoclonal antibody to cross-react against different antigens."
According to the news reporters, the research concluded: "Our results suggest that bond flexibility plays a major role in remodeling antibody-antigen bonds in order to improve recognition during the maturation of the humoral immune system."
For more information on this research see: Bond Elasticity Controls Molecular Recognition Specificity in Antibody-Antigen Binding.
Our news correspondents report that additional information may be obtained by contacting A. Alemany, Inst Salud Carlos III, Networking Res Center Bioengn Biomat & Nanomed CIBER,
Keywords for this news article include: Antibodies, Spain,
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2013, NewsRx LLC
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