By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Nanoparticles. According to news reporting originating from Lanzhou, People's Republic of China, by NewsRx correspondents, research stated, "Based on the characteristics of polycations of chitosan and glucoamylase, which are oppositely charged, they were successfully alternatingly deposited onto the surface of aldehyde-modified Fe3O4 nanoparticles by using a layer-by-layer ion exchange method to form magnetic carriers to construct multilayer films (designated as Fe3O4@(CS/GA)(n)). The (CS/GA)(n) film systems were endowed with the pH-dependent properties of chitosan as well as the catalytic activity of glucoamylase."
Our news editors obtained a quote from the research from Lanzhou University, "The changes in weight loss and surface chemistry, morphology, and magnetic sensitivity were monitored and verified by UV/Vis spectroscopy, zeta potential, TEM, and a vibrating sample magnetometer. Subsequently, the influence of the number of bilayers, storage stability, pH, temperature, and reusability of Fe3O4@(CS/GA)(5) biocatalysts on catalytic activity were investigated. The results from characterization and determination remarkably indicate that Fe3O4@(CS/GA)(5) presents excellent catalytic activity, storage stability, pH stability, and reusability in comparison with free enzyme. Fe3O4@(CS/GA)(5) retained >60% of its initial activity at 65 degrees C over 6h; the optimum temperature and pH also increased to the ranges of 45-65 degrees C and 2.5-3.5, respectively, and only 27% activity was lost after 10cycles."
According to the news editors, the research concluded: "This new strategy simplifies the reaction protocol and improves encapsulation efficiency and catalytic activity for new potential applications in biotechnology."
For more information on this research see: Biocatalytic Performance of pH-Sensitive Magnetic Nanoparticles Derived from Layer-by-Layer Ionic Self-Assembly of Chitosan with Glucoamylase. Chemistry-An Asian Journal, 2013;8(12):3116-3122. Chemistry-An Asian Journal can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany (see also Nanoparticles).
The news editors report that additional information may be obtained by contacting J.Z. Wang, Lanzhou University, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, People's Republic of China. Additional authors for this research include G.H. Zhao, Y.F. Li, X.M. Peng and Y.T. Li.
Keywords for this news article include: Asia, Lanzhou, Glucoamylase, Nanotechnology, Emerging Technologies, Enzymes and Coenzymes, Magnetic Nanoparticles, People's Republic of China
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