The collaboration of TGen, Nemucore and Barrow will pursue ways to optimize targeted therapies delivered by nanotechnology systems to treat glioblastoma, the most common and most aggressive form of malignant brain tumors.
This project is a primary example of translational research, moving laboratory findings as soon as practicable to patient care. Laboratory success should result in eventual follow-on efforts in the biomanufacturing of personalized medicine and implementation of new therapies in clinical trials.
"We are excited about this innovative approach to research, especially the collaboration between two major
One of the goals of this
Each of the collaborators is a leader in their respective fields:
• TGen's genomic sequencing - in which all 3 billion base-pair letters of human DNA are spelled out, in order - can be used to create molecular profiles of patients and match specific therapies to diseases, providing the promise of better clinical results while minimizing side effects.
• Nemucore specializes in the development of life-saving cancer nanomedicines, in which drugs are packaged in ways that evade cancer defenses, delivering medications that can knockout tumors.
• Barrow, which is internationally known for its treatment of neurological disorders and treats one of the highest volumes of brain tumors in
"Working with the research team from the outset of the study will be helpful. We can advise them on methods or components as they develop novel formulations suitable for crossing the blood-brain barrier," said Dr.
Based on the research findings, the team would work with a strategic manufacturing partner, Blue Ocean Biomanufacturing, to develop methods to manufacture personalized medicine for the treatment of glioblastoma.
Coleman also is CEO of
"Barrow's collaboration with TGen and Nemucore is unique in that we will develop novel drug delivery technology that fully spans basic academic science through bench top translation and manufacturing," says Dr.
"This grant is a tremendous step in changing the way medicine is developed in
Keywords for this news article include: Genetics, Oncology, Treatment, Technology,
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2013, NewsRx LLC
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