By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Supramolecular Research is the subject of a report. According to news reporting originating from Nagoya, Japan, by NewsRx correspondents, research stated, "We designed novel peptide gemini surfactants (PG-surfactants), DKDKC12K and DKDKC12D, which can solubilize Photosystem I (PSI) of Thermosynecoccus elongatus and Photosystem II (PSII) of Thermosynecoccus vulcanus in an aqueous buffer solution. To assess the detailed effects of PG-surfactants on the original supramolecular membrane protein complexes and functions of PSI and PSII, we applied the surfactant exchange method to the isolated PSI and PSII."
Our news editors obtained a quote from the research from the Graduate School of Engineering, "Spectroscopic properties, light-induced electron transfer activity, and dynamic light scattering measurements showed that PSI and PSII could be solubilized not only with retention of the original supramolecular protein complexes and functions but also without forming aggregates. Furthermore, measurement of the lifetime of light-induced charge-separation state in PSI revealed that both surfactants, especially DKDKC12D, displayed slight improvement against thermal denaturation below 60 °C compared with that using ?-DDM. This degree of improvement in thermal resistance still seems low, implying that the peptide moieties did not interact directly with membrane protein surfaces. By conjugating an electron mediator such as methyl viologen (MV(2+)) to DKDKC12K (denoted MV-DKDKC12K), we obtained derivatives that can trap the generated reductive electrons from the light-irradiated PSI. After immobilization onto an indium tin oxide electrode, a cathodic photocurrent from the electrode to the PSI/MV-DKDKC12K conjugate was observed in response to the interval of light irradiation."
According to the news editors, the research concluded: "These findings indicate that the PG-surfactants DKDKC12K and DKDKC12D provide not only a new class of solubilization surfactants but also insights into designing other derivatives that confer new functions on PSI and PSII."
For more information on this research see: Application of peptide gemini surfactants as novel solubilization surfactants for photosystems I and II of cyanobacteria. Langmuir, 2013;29(37):11667-80. (American Chemical Society - www.acs.org; Langmuir - www.pubs.acs.org/journal/langd5)
The news editors report that additional information may be obtained by contacting S. Koeda, Graduate School of Engineering, Nagoya Institute of Technology , Gokiso-cho, Showa-ku, Nagoya, Aichi 466-8555, Japan. Additional authors for this research include K. Umezaki, T. Noji, A. Ikeda, K. Kawakami, M. Kondo, Y. Yamamoto, J.R. Shen, K. Taga, T. Dewa, S. Ito, M. Nango, T. Tanaka and T. Mizuno (see also Supramolecular Research).
Keywords for this news article include: Asia, Japan, Nagoya, Nanotechnology, Emerging Technologies, Supramolecular Research.
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