By a News Reporter-Staff News Editor at Health & Medicine Week -- Fresh data on Hematoma are presented in a new report. According to news reporting out of Caen, France, by NewsRx editors, research stated, "The aim of the present study was to investigate the effects of normobaric oxygen (NBO) therapy on T2*-weighted images of intracranial hemorrhages (ICHs). Two common models of ICH were performed in mice, and longitudinal T2*-weighted images of the hematomas were acquired under normoxia or NBO."
Our news journalists obtained a quote from the research from Caen University Hospital, "The effects of NBO were also investigated on perfusion-weighted imaging, susceptibility-weighted imaging, and molecular imaging of vascular cell adhesion molecule-1 after ICH. Last, we performed neurological testing, including neuroscore, actimetry, and gait analysis (Catwalk), to study the influence of NBO on neurological outcome of mice presenting ICH. Our results demonstrated that NBO, even during a short period of time, dramatically reduces the sensitivity of T2*-weighted imaging to detect ICH. Moreover, we provide evidence that the disappearance of ICH on T2*-weighted imaging could be used to improve accuracy of perfusion-weighted imaging and to allow molecular imaging after ICH. Importantly, a 30-minute NBO preparation 24 hours after ICH onset does not influence neurological outcome. We provide an experimental demonstration that NBO significantly affects T2*-weighted imaging in ICH."
According to the news editors, the research concluded: "Although this phenomenon could lead to inaccurate assessment of ICH volume, it could also be safely used to allow perfusion-weighted imaging and molecular imaging."
For more information on this research see: Intracerebral Hematomas Disappear on T2*-Weighted Images During Normobaric Oxygen Therapy. Stroke, 2013;44(12):3482-3489. Stroke can be contacted at: Lippincott Williams & Wilkins, 530 Walnut St, Philadelphia, PA 19106-3621, USA. (Lippincott Williams and Wilkins - www.lww.com; Stroke - stroke.ahajournals.org/)
Our news journalists report that additional information may be obtained by contacting T. Gaberel, Caen Univ Hosp, Biostat & Clin Res Unit, Caen, France. Additional authors for this research include C. Gakuba, M. Hebert, A. Montagne, V. Agin, M. Rubio, E. Emery, D. Vivien and M. Gauberti (see also Hematoma).
Keywords for this news article include: Caen, France, Europe, Therapy, Hematoma, Chalcogens, Nanotechnology, Molecular Imaging, Emerging Technologies
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