By a News Reporter-Staff News Editor at Health & Medicine Week -- Data detailed on Apoptosis have been presented. According to news originating from Ann Arbor, Michigan, by NewsRx correspondents, research stated, "To develop new nanoparticle materials possessing antioxidative capacity with improved physical characteristics, we have studied titanium-doped cerium oxide (CeTiO2) nanoparticles. CeTiO2 nanoparticles had mode diameters in the range of 15-20 nm."
Our news journalists obtained a quote from the research from the University of Michigan, "These nanoparticles demonstrated catalase activity, and did not promote the activation of hemolytic or cytolytic pathways in living cells. Using surface plasmon resonance-enhanced microscopy, we find that these nanoparticles associate with cells. Transmission electron microscopy studies demonstrated that these nanoparticles accumulate within the vacuolar compartment of cells. Importantly, CeTiO2 nanoparticles decrease hydrogen peroxide-mediated apoptosis of cells as judged by the reduced cleavage of a caspase 3-sensitive label."
According to the news editors, the research concluded: "CeTiO2 nanoparticles may contribute to deflecting tissue damage in a broad spectrum of oxidant-mediated diseases, such as macular degeneration and Alzheimer's disease."
For more information on this research see: Titanium-doped cerium oxide nanoparticles protect cells from hydrogen peroxide-induced apoptosis. Journal of Nanoparticle Research, 2013;15(12):1-9. Journal of Nanoparticle Research can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands. (Springer - www.springer.com; Journal of Nanoparticle Research - www.springerlink.com/content/1388-0764/)
The news correspondents report that additional information may be obtained from A. Clark, University of Michigan, Sch Med, Dept. of Ophthalmol & Visual Sci, Ann Arbor, MI 48105, United States. Additional authors for this research include A.P. Zhu and H.R. Petty (see also Apoptosis).
Keywords for this news article include: Gases, Anions, Cerium, Michigan, Titanium, Ann Arbor, Apoptosis, Chemistry, Electrolytes, Light Metals, Nanoparticle, United States, Nanotechnology, Hydrogen Peroxide, Inorganic Chemicals, Emerging Technologies, Reactive Oxygen Species, North and Central America, Lanthanoid Series Elements
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