By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Supramolecular Research. According to news reporting out of Eindhoven, Netherlands, by NewsRx editors, research stated, "In the past decade, significant progress has been made in the field of biomaterials, for potential applications in tissue engineering or drug delivery. We have recently developed a new class of thermoplastic elastomers, based on ureidopyrimidinone (UPy) quadruple hydrogen bonding motifs."
Our news journalists obtained a quote from the research from the Eindhoven University of Technology, "These supramolecular polymers form nanofiber-like aggregates initially via the dimerization of the UPy units followed by lateral urea-hydrogen bonding. Combined kinetic and thermodynamic studies unravel the pathway complexity in the formation of these polymorphic nanofibers and the subtlety of the polymer's design, while these morphologies are so critically important when these materials are used in combination with cells. We also show that the cell behavior directly depends on the length and shape of the nanofibers, illustrating the key importance of macromolecular and supramolecular organization of biomaterials."
According to the news editors, the research concluded: "This study leads to new design rules that determine what factors are decisive for a polymer to be a good candidate as biomaterial."
For more information on this research see: From Molecular Structure to Macromolecular Organization: Keys to Design Supramolecular Biomaterials. Macromolecules, 2013;46(21):8528-8537. Macromolecules can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Macromolecules - www.pubs.acs.org/journal/mamobx)
Our news journalists report that additional information may be obtained by contacting M. Hutin, Eindhoven University of Technology, Lab Macromol & Organ Chem, NL-5600 MB Eindhoven, Netherlands. Additional authors for this research include E. Burakowska-Meise, W.P.J. Appel, P.Y.W. Dankers and E.W. Meijer (see also Supramolecular Research).
Keywords for this news article include: Europe, Eindhoven, Nanofiber, Netherlands, Nanotechnology, Emerging Technologies, Supramolecular Research
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