By a News Reporter-Staff News Editor at Health & Medicine Week -- Fresh data on Optical Coherence Tomography are presented in a new report. According to news originating from Songnam, South Korea, by NewsRx correspondents, research stated, "Our aim was to evaluate and compare diagnostic capabilities of time-domain (Stratus) and spectral-domain (Cirrus) optical coherence tomography (OCT) to detect diffuse retinal nerve fiber layer (RNFL) atrophy. This study assessed 101 eyes from 101 glaucoma patients with diffuse RNFL atrophy and 101 eyes from 101 age-matched healthy individuals."
Our news journalists obtained a quote from the research from Seoul National University, "Two experienced glaucoma specialists graded red-free RNFL photographs of eyes with diffuse RNFL atrophy using a four-level grading system. The area under the receiver operating characteristic curves (AUC) of normal eyes was compared with that of eyes with diffuse atrophy. Sensitivity and specificity of each OCT device were calculated on the basis of its internal normative database. The largest AUC for Stratus and Cirrus were obtained for average RNFL thicknesses (0.96 and 0.94, respectively). Comparison of the AUC with different RNFL atrophy grades revealed no significant difference between the two OCT devices. Using an internal normative database at a< 5 % level, the overall sensitivity of Stratus ranged from 58.0 to 84.0 %, whereas that of Cirrus ranged from 75.0 to 87.0 %. According to the normative database, the highest Stratus sensitivity was obtained with the temporal-superior-nasal-inferior-temporal (TSNIT) thickness graph, and the highest Cirrus sensitivity with the TSNIT thickness graph and the deviation map. The AUC obtained from Cirrus were comparable with those from Stratus. On the basis of their normative databases, these devices had similar diagnostic accuracy."
According to the news editors, the research concluded: "Our results suggest that the diagnostic capabilities of the two instruments to detect diffuse RNFL atrophy are similar."
For more information on this research see: Comparison of ability of time-domain and spectral-domain optical coherence tomography to detect diffuse retinal nerve fiber layer atrophy. Japanese Journal of Ophthalmology, 2013;57(6):529-539. Japanese Journal of Ophthalmology can be contacted at: Springer Japan Kk, Chiyoda First Bldg East, 3-8-1 Nishi-Kanda, Chiyoda-Ku, Tokyo, 101-0065, Japan. (Springer - www.springer.com; Japanese Journal of Ophthalmology - www.springerlink.com/content/0021-5155/)
The news correspondents report that additional information may be obtained from K.E. Kim, Seoul National University, Bundang Hosp, Dept. of Ophthalmol, Songnam, South Korea. Additional authors for this research include S.H. Kim, J.W. Jeoung, K.H. Park, T.W. Kim and D.M. Kim (see also Optical Coherence Tomography).
Keywords for this news article include: Asia, Songnam, South Korea, Imaging Technology, Optical Coherence Tomography
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