By a News Reporter-Staff News Editor at Biotech Business Week -- Researchers detail new data in DNA Research. According to news reporting out of Perth, Australia, by NewsRx editors, research stated, "We determined a series of quality control (QC) analyses to assess the usability of DNA collected and processed from different countries utilizing different DNA extraction techniques prior to genome-wide association studies (GWAS). The quality of DNA collected utilizing four different DNA extraction techniques and the impact of shipping DNA at different temperatures on array performance were evaluated."
Our news journalists obtained a quote from the research from the University of Western Australia, "Fifteen maternal-fetal pairs were used from four countries. DNA was extracted using four approaches: whole blood, blood spots with whole genome amplification (WGA), saliva and buccal swab. Samples were sent to a genotyping facility, either on dry ice or at room temperature and genotyped using Affymetrix SNP array 6.0. QC measured included extraction techniques, effect of shipping temperatures, accuracy and Mendelian concordance. Significantly fewer (50 % ) single nucleotide polymorphisms (SNPs) passed QC metrics for buccal swab DNA (p
According to the news editors, the research concluded: "DNA extracted from blood, saliva and blood spots were found suitable for GWAS in our study."
For more information on this research see: Preterm Birth Genome Project (PGP) -- validation of resources for preterm birth genome-wide studies. Journal of Perinatal Medicine, 2013;41(1):45-9. Journal of Perinatal Medicine can be contacted at: Walter de Gruyter GmbH & Co. KG, Genthiner Strasse 13, D-10785 Berlin, Germany (see also DNA Research).
Our news journalists report that additional information may be obtained by contacting C.E. Pennell, School of Women’s and Infants’ Health, The University of Western Australia, Perth, Australia. Additional authors for this research include F. Vadillo-Ortega, D.M. Olson, E.H. Ha, S. Williams, T.M. Frayling, S. Dolan, M. Katz, M. Merialdi and R. Menon.
Publisher contact information for the Journal of Perinatal Medicine is: Walter de Gruyter GmbH & Co. KG, Genthiner Strasse 13, D-10785 Berlin, Germany.
Keywords for this news article include: Perth, DNA Research, Australia and New Zealand.
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