By a News Reporter-Staff News Editor at Women's Health Weekly -- Current study results on Engineering have been published. According to news reporting originating from Morgantown, West Virginia, by NewsRx correspondents, research stated, "The continued development and use of engineered nanomaterials (ENM) has given rise to concerns over the potential for human health effects. Although the understanding of cardiovascular ENM toxicity is improving, one of the most complex and acutely demanding 'special' circulations is the enhanced maternal system to support fetal development."
Our news editors obtained a quote from the research from the University of Virginia, "The Barker hypothesis proposes that fetal development within a hostile gestational environment may predispose/program future sensitivity. Therefore, the objective of this study was 2-fold: (1) to determine whether maternal ENM exposure alters uterine and/or fetal microvascular function and (2) test the Barker hypothesis at the microvascular level. Pregnant (gestation day 10) Sprague-Dawley rats were exposed to nano-titanium dioxide aerosols (11.3 +/- 0.039 mg/m(3)/hr, 5 hr/d, 8.2 +/- 0.85 days) to evaluate the maternal and fetal microvascular consequences of maternal exposure. Microvascular tissue isolation (gestation day 20) and arteriolar reactivity studies (
According to the news editors, the research concluded: "To our knowledge, this is the first report to provide evidence that maternal ENM inhalation is capable of influencing fetal health and that the Barker hypothesis is applicable at the microvascular level."
For more information on this research see: Maternal engineered nanomaterial exposure and fetal microvascular function: does the Barker hypothesis apply? American Journal of Obstetrics and Gynecology, 2013;209(3):148-158. American Journal of Obstetrics and Gynecology can be contacted at: Mosby-Elsevier, 360 Park Avenue South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; American Journal of Obstetrics and Gynecology - www.elsevier.com/wps/product/cws_home/623277)
The news editors report that additional information may be obtained by contacting P.A. Stapleton, West Virginia Univ Sch Med, Dept. of Physiol & Pharmacol, Morgantown, WV, United States. Additional authors for this research include V.C. Minarchick, J.H. Yi, K. Engels, C.R. McBride and T.R. Nurkiewicz (see also Engineering).
Keywords for this news article include: Morgantown, Engineering, West Virginia, United States, North and Central America
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