By a News Reporter-Staff News Editor at Medical Letter on the CDC & FDA -- Current study results on Influenza A Virus Subtype H1N1 have been published. According to news reporting originating from Kongens Lyngby, Denmark, by NewsRx correspondents, research stated, "Influenza infections are associated with high morbidity and mortality, carry the risk of pandemics, and pose a considerable economic burden worldwide. To improve the management of the illness, it is essential with accurate and fast point-of-care diagnostic tools for use in the field or at the patient's bedside."
Our news editors obtained a quote from the research from the Technical University of Denmark, "Conventional diagnostic methods are time consuming, expensive and require specialized laboratory facilities. We present a highly sensitive, highly specific, and low cost platform to test for acute virus infections in less than 15 min, employing influenza A virus (H1N1) as an example of its usability. An all polymer microfluidic system with a functionalized conductive polymer (PEDOT-OH:TsO) microelectrode array was developed and exploited for label free and real time electrochemical detection of intact influenza A virus (H1N1) particles. DNA aptamers with affinity for influenza A virus (H1N1) were linked covalently to the conductive polymer microelectrodes in the microfluidic channel. Based on changes in the impedance when virions were captured by immobilized probes, we could detect clinically relevant concentrations of influenza A virus (H1N1) in saliva."
According to the news editors, the research concluded: "This is a new, stable and very sensitive point-of-care platform for detection and diagnostics of intact virus particles."
For more information on this research see: High sensitivity point-of-care device for direct virus diagnostics. Biosensors & Bioelectronics, 2013;49():374-9. (Elsevier - www.elsevier.com; Biosensors & Bioelectronics - www.elsevier.com/wps/product/cws_home/405913)
The news editors report that additional information may be obtained by contacting K. Kiilerich-Pedersen, Technical University of Denmark, Dept. of Micro- and Nanotechnology, Oersteds Plads 345 East, DK-2800 Kongens Lyngby, Denmark. Additional authors for this research include J. Dapra, S. Cherre and N. Rozlosnik (see also Influenza A Virus Subtype H1N1).
Keywords for this news article include: Europe, Denmark, Virology, Swine Flu, RNA Viruses, Kongens Lyngby, Swine Influenza, Orthomyxoviridae, Infectious Disease, Vertebrate Viruses, Influenza A Virus Subtype H1N1.
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