By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Nanoparticles are discussed in a new report. According to news reporting originating from Tampere, Finland, by NewsRx correspondents, research stated, "The potential impact of nanoparticles on the environment and on human health has attracted considerable interest worldwide. The amount of transcriptomics data, in which tissues and cell lines are exposed to nanoparticles, increases year by year."
Our news editors obtained a quote from the research from the Tampere University of Technology, "In addition to the importance of the original findings, this data can have value in broader context when combined with other previously acquired and published results. In order to facilitate the efficient usage of the data, we have developed the NanoMiner web resource (http://nanominer.cs.tut.fi/), which contains 404 human transcriptome samples exposed to various types of nanoparticles. All the samples in NanoMiner have been annotated, preprocessed and normalized using standard methods that ensure the quality of the data analyses and enable the users to utilize the database systematically across the different experimental setups and platforms. With NanoMiner it is possible to 1) search and plot the expression profiles of one or several genes of interest, 2) cluster the samples within the datasets, 3) find differentially expressed genes in various nanoparticle studies, 4) detect the nanoparticles causing differential expression of selected genes, 5) analyze enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and Gene Ontology (GO) terms for the detected genes and 6) search the expression values and differential expressions of the genes belonging to a specific KEGG pathway or Gene Ontology."
According to the news editors, the research concluded: "In sum, NanoMiner database is a valuable collection of microarray data which can be also used as a data repository for future analyses."
For more information on this research see: NanoMiner - integrative human transcriptomics data resource for nanoparticle research. Plos One, 2013;8(7):e68414. (Public Library of Science - www.plos.org; Plos One - www.plosone.org)
The news editors report that additional information may be obtained by contacting L. Kong, Dept. of Signal Processing, Tampere University of Technology, Tampere, Finland. Additional authors for this research include S. Tuomela, L. Hahne, H. Ahlfors, O. Yli-Harja, B. Fadeel, R. Lahesmaa and R. Autio (see also Nanoparticles).
Keywords for this news article include: Europe, Tampere, Finland, Nanotechnology, Emerging Technologies.
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