By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Essential Amino Acids. According to news originating from Namur, Belgium, by NewsRx correspondents, research stated, "A biocompatible modified carbon paste electrode (CPE) for the selective detection of L-Tryptophan (Trp) at physiological pH in the presence of Ascorbic acid (AA), Dopamine (DA) and Uric acid (UA) has been constructed. The surface of CPE was modified with a combination of two modifiers such as the multiwalled carbon nanotubes and Mg-Al-CO3 layered double hydroxide by drop cast method."
Our news journalists obtained a quote from the research from the University of Notre Dame, "The surface morphology of the electrodes was studied using FE-SEM images. The Nyquist plots reveal the least charge transfer resistance for the modified electrode. The electrochemical behaviour of the modified electrode was investigated using the cyclic voltammetry method. A very little amount of the modifiers was enough to bring about an excellent sensitivity and electrocatalytic activity towards the oxidation of Trp. Trp exhibits an irreversible electrochemical charge transfer. The quantification of Trp was done by hydrodynamic linear sweep voltammetry using the rotated modified electrode. Two wide linear response ranges were observed for Trp between 3-90 mu M and 90-1000 mu M with a lower detection limit of 6.8 x 10(-9) M (SIN= 3). A large peak separation between Trp and the interfering molecules, good sensitivity and stability enable the modified electrode to be amenable for use in the analysis of Trp individually and in the simultaneous presence of AA, DA and UA at physiological pH. The practical application was successfully demonstrated by estimating Trp in spiked milk and the blood serum."
According to the news editors, the research concluded: "The modified electrode has all the characteristics to be used as a potential sensor for the analysis of Trp in real samples."
For more information on this research see: Electrochemical determination of L-Tryptophan based on a multiwall carbon nanotube/Mg-Al layered double hydroxide modified carbon paste electrode as a sensor. Journal of Electroanalytical Chemistry, 2013;704():220-226. Journal of Electroanalytical Chemistry can be contacted at: Elsevier Science Sa, PO Box 564, 1001 Lausanne, Switzerland (see also Essential Amino Acids).
The news correspondents report that additional information may be obtained from O.J. D'Souza, Fac Univ Notre Dame Paix, Lab Chim & Electrochim Surface, B-5000 Namur, Belgium. Additional authors for this research include R.J. Mascarenhas, T. Thomas, I.N.N. Namboothiri, M. Rajamathi, P. Martis and J. Dalhalle.
Keywords for this news article include: Namur, Europe, Anions, Belgium, Alkalies, Chemistry, Fullerenes, Hydroxides, Tryptophan, Nanotechnology, Electrochemical, Inorganic Chemicals, Aromatic Amino Acids, Emerging Technologies, Essential Amino Acids, Multiwalled Carbon Nanotube
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