By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Biotechnology is the subject of a report. According to news reporting from Guangdong, People's Republic of China, by NewsRx journalists, research stated, "The outer membrane proteins of Vibrio alginolyticus play an important role in the virulence of the bacterium and are potential candidates for vaccine development. In the present study, the ompW gene was cloned, expressed and purified."
The news correspondents obtained a quote from the research from the Zhongkai University of Agriculture and Technology, "A DNA vaccine was constructed by inserting the ompW gene into a pcDNA plasmid. Crimson snapper Lutjanus erythropterus (Bloch) were injected intramuscularly with the recombinant plasmid pcDNA-ompW. The expression of the DNA vaccine was detected in gill, head kidney, heart, liver, spleen and injection site muscle of crimson snapper by RT-PCR 7 and 28 d post-vaccination. The ELISA results demonstrated that the DNA vaccine produced an observable antibody response in all sera of the vaccinated fish."
According to the news reporters, the research concluded: "In addition, crimson snapper immunized with the DNA vaccine showed a relative percentage survival (RPS) of 92.53%, indicating effective protection against V. alginolyticus infection."
For more information on this research see: Protection against Vibrio alginolyticus in crimson snapper Lutjanus erythropterus immunized with a DNA vaccine containing the ompW gene. Diseases of Aquatic Organisms, 2013;106(1):39-47. Diseases of Aquatic Organisms can be contacted at: Inter-Research, Nordbunte 23, D-21385 Oldendorf Luhe, Germany. (Inter-Research Science Center - www.int-res.com; Diseases of Aquatic Organisms - www.int-res.com/journals/dao/dao-home/)
Our news journalists report that additional information may be obtained by contacting S.H. Cai, Zhongkai Univ Agr & Engn, Guangzhou 510225, Guangdong, People's Republic of China. Additional authors for this research include Y.S. Lu, J.C. Jian, B. Wang, Y.C. Huang, J.F. Tang, Y. Ding and Z.H. Wu (see also technology.html">Biotechnology).
Keywords for this news article include: Asia, Biotechnology, Guangdong, DNA Research, DNA Vaccines, Vibrionaceae, Synthetic Vaccines, Gammaproteobacteria, Vibrio alginolyticus, Gram-Negative Bacteria, People's Republic of China, Gram-Negative Facultatively Anaerobic Rods
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