By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Immunology. According to news originating from Okayama, Japan, by NewsRx correspondents, research stated, "Ion exchange is a simple and efficient method for separating no-carrier-added Cu-64 from an irradiated Ni target. We developed a semi-automated two-round Cu-64 separation system equipped with a strong-base anion exchange resin column."
Our news journalists obtained a quote from the research from Okayama University, "We first verified the efficiency of the system using a non-radioactive substitute consisting of 25 mg of Ni and 127 ng of Cu, and confirmed that Cu was completely eluted at the second round of the separation step. After the bombardment, separation of Cu-64 from the Ni target was achieved with high radiochemical purity. Cu-64 produced and separated in this study had an extremely low level of Ni impurity."
According to the news editors, the research concluded: "It could be used for labeling monoclonal antibodies for antibody positron emission tomography imaging and synthesizing radiopharmaceuticals."
For more information on this research see: A purification system for Cu-64 produced by a biomedical cyclotron for antibody PET imaging. Journal of Radioanalytical and Nuclear Chemistry, 2013;298(1):295-300. Journal of Radioanalytical and Nuclear Chemistry can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands. (Springer - www.springer.com; Journal of Radioanalytical and Nuclear Chemistry - www.springerlink.com/content/0236-5731/)
The news correspondents report that additional information may be obtained from T. Toyota, Okayama University, Collaborat Res Center Okayama Med Innovat Center, Grad Sch Med Dental & Pharmaceut Sci, Kita Ku, Okayama 7008558, Japan. Additional authors for this research include T. Hanafusa, T. Oda, I. Koumura, T. Sasaki, E. Matsuura, H. Kumon, T. Yano and T. Ono (see also Immunology).
Keywords for this news article include: Asia, Antibodies, Japan, Okayama, Immunology, Blood Proteins, Immunoglobulins
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