By a News Reporter-Staff News Editor at Cardiovascular Week -- Current study results on Cardiovascular Diseases and Conditions have been published. According to news reporting out of Berlin, Germany, by NewsRx editors, research stated, "Cardiovascular diseases remain the leading cause of morbidity and mortality in the Western world and developing countries. In clinical practice, in vivo characterization of atherosclerotic lesions causing myocardial infarction, ischemic stroke, and other complications remains challenging."
Our news journalists obtained a quote from the research from the Charite University Hospital and School of Medicine, "Imaging methods, limited to the assessment luminal stenosis, are the current reference standard for the assessment of clinically significant coronary and carotid artery disease and the guidance of treatment. These techniques do not allow distinction between stable and potentially vulnerable atherosclerotic plaque. Magnetic resonance (MR) imaging is a modality well suited for visualization and characterization of the relatively thin arterial vessel wall, because it allows imaging with high spatial resolution and excellent soft-tissue contrast. In clinical practice, atherosclerotic plaque components of the carotid artery and aorta may be differentiated and characterized by using unenhanced vessel wall MR imaging. Additional information can be gained by using clinically approved nonspecific contrast agents. With the advent of targeted MR contrast agents, which enhance specific molecules or cells, pathologic processes can be visualized at a molecular level with high spatial resolution. In this article, the pathophysiologic changes of the arterial vessel wall underlying the development of atherosclerosis will be first reviewed. Then basic principles and properties of molecular MR imaging contrast agents will be introduced. Additionally, recent advances in preclinical molecular vessel wall imaging will be reviewed."
According to the news editors, the research concluded: "Finally, the clinical feasibility of arterial vessel wall imaging at unenhanced and contrast material-enhanced MR imaging of the aortic, carotid, and coronary vessel wall will be discussed."
For more information on this research see: MR Imaging of the Arterial Vessel Wall: Molecular Imaging from Bench to Bedside. Radiology, 2013;269(1):33-50. Radiology can be contacted at: Radiological Soc North America, 820 Jorie Blvd, Oak Brook, IL 60523, USA. (Hindawi Publishing - www.hindawi.com; Radiology - www.hindawi.com/journals/rrp/)
Our news journalists report that additional information may be obtained by contacting M.R. Makowski, Charite, Dept. of Radiol, Berlin, Germany (see also Cardiovascular Diseases and Conditions).
Keywords for this news article include: Berlin, Europe, Germany, Angiology, Cardiology, Nanotechnology, Atherosclerosis, Molecular Imaging, Emerging Technologies, Cardiovascular Diseases and Conditions
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