Company to unveil results from recent studies during upcoming CHI
Digital PCR ConferenceA wide dynamic range of six logs, enabling scientists to detect
very low and very high abundance targets at the same time. This level
of performance is crucial in many viral load detection applications,
such as HIV and HPV studies where dose can vary greatly and
emerging minor drug resistant strains need to be quantitatively
Multiplex analysis of four different gene targets. Uniquely,
the RainDrop System allows multiplexing of up to 12 targets, which is
critical for broad deployment of gene expression based prognostic
Detection of very subtle RNA level changes (+/- 10 percent).
This will help transform applications such as neurobiology, where
small changes in expression levels can have large effects.
BILLERICA, Mass.--(BUSINESS WIRE)--
Technologies, Inc today announced that it has added one-step single
molecule RNA detection capabilities to its RainDrop™
Digital PCR System. The new workflow provides researchers with a
simple method of counting individual RNA target molecules. Available
immediately to all current and future RainDrop customers, the new
capabilities are compatible with existing one-step master mix solutions
and a range of qPCR probes.
“Digital single molecule counting of RNA molecules is ultimately the
most precise, sensitive and accurate means of analysis. Other methods,
such as RNA sequencing, have many processing and amplification steps
that introduce significant bias,” said Andrew Watson, Chief Commercial
Officer, RainDance Technologies. “By adding single molecule RNA
detection capabilities, the RainDrop Digital PCR System now provides the
industry’s most cost-effective and deployable means of digital counting
of RNA molecules.”
Transforming Traditional RNA Studies
The RainDrop System provides unique and enabling performance for RNA
analysis. During the CHI Digital PCR Conference, extensive experimental
data will be presented showing:
The RainDrop Digital PCR System is also transforming molecular analysis
by enabling digital answers across a number of other applications.
Today’s announcement follows other recent published customer successes:
in Journal of Clinical Chemistry demonstrated the use of
the RainDrop Digital PCR system to detect multiple KRAS mutations
directly from a liquid biopsy.
from the Massachusetts General Hospital demonstrated the use of a
RainDrop Digital PCR System to detect glioma-associated mRNA mutations
from cerebrospinal fluid.
Inc. recently demonstrated that BRAF mutations present in
trans-renal DNA from urine can be measured with unprecedented
sensitivity by the RainDrop Digital PCR System.