By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Tetracyclines. According to news reporting out of Tianjin, People's Republic of China, by NewsRx editors, research stated, "Zeolite imidazolate framework-8 (ZIF-8) was used as the novel sorbent for on-line solid-phase extraction coupled with high-performance liquid chromatography (HPLC) for the determination of oxytetracycline (OTC), tetracycline (TC) and chlorotetracycline (CTC) in water and milk samples. 390 mg of ZIF-8 was packed into a stainless steel column (3 cm long x 4.6 mm i.d.) which was mounted on the HPLC injector valve to replace the sample loop. On-line solid-phase extraction of OTC, TC and CTC was achieved by loading sample solution at a flow rate of 3.0 mL min(-1) for 10 min with the aid of a flow-injection system."
Our news journalists obtained a quote from the research from Nankai University, "The extracted analytes were subsequently eluted into a C-18 analytical column (25 cm long x 4.6 mm i.d.) for HPLC separation under isocratic condition with a mobile phase (10% MeOH-20%ACN-70% 0.02 mol L-1 oxalic acid solution) at a flow rate of 1.0 mL min(-1). Under optimized conditions, the developed method gave the enhancement factors of 35-61, the linearity range of 5-1000 mu g L-1, the detection limits of 1.5-8.0 mu g L-1, quantification limits of 5.0-26.7 mu g L-1, uncertainties of 0.9-1.1 mu g L-1, and the sample throughput of 4 samples h(-1)."
According to the news editors, the research concluded: "The recoveries of OTC, TC and CTC at 50 mu g L-1 in water and milk samples ranged from 70.3% to 107.4%."
For more information on this research see: Zeolite imidazolate framework-8 as sorbent for on-line solid-phase extraction coupled with high-performance liquid chromatography for the determination of tetracyclines in water and milk samples. Journal of Chromatography A, 2013;1304():28-33. Journal of Chromatography A can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Journal of Chromatography A - www.elsevier.com/wps/product/cws_home/502688)
Our news journalists report that additional information may be obtained by contacting X.Q. Yang, Nankai Univ, Coll Chem, Res Center Analyt Sci, Tianjin 300071, People's Republic of China. Additional authors for this research include C.X. Yang and X.P. Yan (see also Tetracyclines).
Keywords for this news article include: Asia, Tianjin, Hydrocarbons, Naphthacenes, Tetracyclines, Imaging Technology, People's Republic of China, High-Performance Liquid Chromatography
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