In an Original Science Program talk entitled "Application Accuracy of a Second Generation Interventional MRI Stereotactic Platform: Initial Experience in 101 DBS Electrode Implantations," Dr.
• 98% of electrodes were placed with a single pass into the brain;• No electrodes have required repositioning;• The average accuracy of the electrode placement was 0.6 millimeter;• Average surgical times were 3 hours 4 minutes for bilateral cases and 2 hours 23 minutes for unilateral cases.
"Almost every electrode was placed with a single pass to the brain," Dr. Larson stated after his presentation, "meaning we hit the target the first time in each of those cases. More importantly, we hit the correct target based on the fact that no patients have returned for repositioning. We were able to do this through real-time image guidance enabled by ClearPoint."
During a reception sponsored by
• Patients' motor symptom scores improved an average of 72% on the Unified Parkinson's Disease Rating Scale (UPDRS), when comparing their pre-operative "off medication" UPDRS scores to their post-operative "on medication" UPDRS scores;• Patients' post-operative Levodopa dosages decreased by an average of 71% from their pre-operative dosages.
"We've been very impressed with the outcomes we have seen so far," said Dr. Gupta. "My patients have had dramatic improvement in their movement scores. Many of these patients would not have had the awake surgery, so these results were made possible by iMRI asleep DBS."
"While our data is preliminary at this point, I can say that the patients we've assessed so far are doing very well," Dr. Ostrem stated. "Initial clinical outcomes are in line with outcomes in conventional awake procedures, which is exactly what we want to see at this point."
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