Researchers from the
They are biologically degradable and disintegrate in the body after deployment.
Polymers are used to stabilize the nano-envelope, which is furnished with molecules highly specific to and recognized by tumor cells. The envelope of the nanoparticle - experts call it the vesicles - is constructed similarly that of a cell.
The scientists load these carriers with doxorubicin, one of the anti-cancer agents frequently used in chemotherapy. Sodium tetradecyl sulfate (STS), a surfactant, helps the active agent to be absorbed better.
The researchers have already been able to prove the efficacy of their approach in laboratory tests.
He said that they each react very differently to doxorubicin. HCT116 cells are sensitive to the substance, in contrast to HeLa cells. We ran the experiments with pharmacologically relevant dosages, used by clinicians.
Storsberg asserted that the doxorubicin was added to the cell cultures both directly and encapsulated in the nano-carriers.
He developed the new therapy jointly with Dr.
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