By a News Reporter-Staff News Editor at Science Letter -- A new study on Nanoparticles is now available. According to news reporting from Stanford, California, by NewsRx journalists, research stated, "High resolution electron microscopy has been applied to study the structure of metallic nanoparticles. These have sparked considerable interest as contrast agents in the held of biological imaging, including in magnetic resonance imaging (MRI) and computed tomography (CT)."
The news correspondents obtained a quote from the research from Stanford University, "Here, we describe a method of synthesizing sub-10 rim superparamagnetic metal and alloy nanoparticles by reduction of metallic salts. Annealing at 900 degrees C in a methane/hydrogen environment forms a thin graphitic-carbon shell which is expected to improve stability, biocompatibility, and functionalization. Subsequent high resolution electron microscopy verifies graphitization and allows for crystallographic analysis. Most particles consist of single crystals in the phase predicted for the bulk material at the annealing temperature. Electron energy loss spectroscopy, energy dispersive X-ray spectroscopy and lattice constant measurements show large variation in composition for alloy nanoparticles from a single synthesis. The magnetization relaxation time (T-2) measurements demonstrate that Fe and AuFe nanoparticles compete with commercially available iron oxide MRI contrast agents. X-ray attenuation measurements of an AuFe alloy nanoparticle solution gave a relative radiodensity of 280 Hounsfield Units, demonstrating promise as a dual-purpose contrast agent in CT and MRI."
According to the news reporters, the research concluded: "Long term stability in an atmospheric environment was also tested, with no signs of corrosion or oxidation after several years of storage."
For more information on this research see: HREM analysis of graphite-encapsulated metallic nanoparticles for possible medical applications. Ultramicroscopy, 2013;134():167-174. Ultramicroscopy can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands (see also Nanoparticles).
Our news journalists report that additional information may be obtained by contacting R. Sinclair, Stanford University, Dept. of Chem, Stanford, CA 94305, United States. Additional authors for this research include H. Li, S. Madsen and H.J. Dai.
Keywords for this news article include: Stanford, California, United States, Nanotechnology, Emerging Technologies, North and Central America
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2013, NewsRx LLC