By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Enzymes and Coenzymes. According to news originating from Geesthacht, Germany, by NewsRx correspondents, research stated, "Here, we report development of a novel biofunctionalized nanofibrous membrane which, despite its macroporous structure, is able to separate even trace amounts (as low as 2mg/L) of biomolecules such as protein and enzyme from water with an optimum efficiency of ~90%. Such an extraordinary protein selectivity at this level of pollutant concentration for a nanofibrous membrane has never been reported."
Our news journalists obtained a quote from the research from the Institute of Polymer Research, "In the current study, poly(acrylonitrile-co-glycidyl methacrylate) (PANGMA) electrospun nanofibers are functionalized by a bovine serum albumin (BSA) protein. This membrane is extraordinarily successful in removal of BSA protein and Candida antarctica Lipase B (Cal-B) enzyme from a water based solution. Despite a negligible non-specific adsorption of both BSA and Cal-B to the PANGMA nanofibrous membrane (8%), the separation efficiency of the biofunctionalized membrane for BSA and Cal-B reaches to 88% and 81%, respectively. The optimum separation efficiency at a trace amount of protein models is due to the water-induced conformational change of the biofunctional agent. The conformational change not only exposes more functional groups available to catch the biomolecules but also leads to swelling of the nanofibers thereby a higher steric hindrance for the solutes."
According to the news editors, the research concluded: "Besides the optimum selectivity, the biofunctionalized membranes are highly wettable thereby highly water permeable."
For more information on this research see: Biofunctionalized nanofibrous membranes as super separators of protein and enzyme from water. Journal of Colloid and Interface Science, 2013;406():86-93. (Elsevier - www.elsevier.com; Journal of Colloid and Interface Science - www.elsevier.com/wps/product/cws_home/622861)
The news correspondents report that additional information may be obtained from S. Homaeigohar, Helmholtz-Zentrum Geesthacht, Institute of Polymer Research, Geesthacht, Germany. Additional authors for this research include T. Dai and M. Elbahri (see also Enzymes and Coenzymes).
Keywords for this news article include: Europe, Germany, Geesthacht, Enzymes and Coenzymes.
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