By a News Reporter-Staff News Editor at Health & Medicine Week -- Researchers detail new data in Optical Coherence Tomography. According to news originating from Tehran, Iran, by NewsRx correspondents, research stated, "To study the optical coherence tomography (OCT) characteristics in children with optic pathway glioma (OPG) to determine if OCT changes occur alongside clinical/radiological changes at diagnosis and during the second-year follow-up. Twenty-three patients (38 eyes) diagnosed with symptomatic OPG in a single institution were enrolled in this longitudinal observational cohort study."
Our news journalists obtained a quote from the research from Farabi Eye Research Center, "Complete ophthalmologic evaluation, including determination of visual acuity, visual fields, retinal nerve fiber layer ,and posterior pole retinal thickness scanning with spectral-domain optical coherence tomography, and neuroimaging was performed at the time of diagnosis and 6 months and 1 and 2 years after presentation. Patients who experienced visual decline or radioagraphic tumor enlargement of the OPG were classified as progressors. OCT data were compared between progressors and nonprogressors. The average age at diagnosis was 5.8 years. All patients were followed up for 24 months. Five patients (21 %) (eight eyes) had clinical or radiological progression of their OPG during follow-up and were classified as progressors. Mean changes in average nerve fiber layer and posterior pole retinal thickness were significantly higher for progressors compared with nonprogressors (P < 0.001). The area under the receiver operator characteristic curves comparing average nerve fiber layer and posterior pole retinal thinning between the progressors and nonprogressors were 0.94 and 0.95 respectively."
According to the news editors, the research concluded: "Optical coherence tomography of average nerve fiber layer and posterior pole retinal thickness may be helpful in monitoring OPG."
For more information on this research see: Correlation of optical coherence tomography parameters with clinical and radiological progression in patients with symptomatic optic pathway gliomas. Graefes Archive for Clinical and Experimental Ophthalmology, 2013;251(10):2429-2436. Graefes Archive for Clinical and Experimental Ophthalmology can be contacted at: Springer, 233 Spring St, New York, NY 10013, USA (see also Optical Coherence Tomography).
The news correspondents report that additional information may be obtained from M.A. Fard, Farabi Eye Res Center, Tehran 1336616351, Iran. Additional authors for this research include S. Fakhree and B. Eshraghi.
Keywords for this news article include: Iran, Asia, Tehran, Imaging Technology, Optical Coherence Tomography
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