By a News Reporter-Staff News Editor at Health & Medicine Week -- New research on Bone Research is the subject of a report. According to news reporting originating in Geesthacht, Germany, by NewsRx journalists, research stated, "Despite its non-matching mechanical properties titanium remains the preferred metal implant material in orthopaedics. As a consequence in some cases stress shielding effect occurs, leading to implant loosening, osteopenia, and finally revision surgery."
The news reporters obtained a quote from the research from Institute for Materials Research, "Porous metal scaffolds to allow easier specialised cells ingrowth with mechanical properties closer to the ones of bone can overcome this problem. This should improve healing processes, implant integration, and dynamic strength of implants retaining. Three Ti-6Al-4V materials were metal injection moulded and tailored porosities were effectively achieved. After microstructural and mechanical characterisation, two different primary cells of mesenchymal origin (human umbilical cord perivascular cells and human bone derived cells which revealed to be two pertinent models) as well as one cell line originated from primary osteogenic sarcoma, Saos-2, were bestowed to investigate cell-material interaction on genomic and proteome levels. Biological examinations disclosed that no material has negative impact on early adhesion, proliferation or cell viability."
According to the news reporters, the research concluded: "An efficient cell ingrowth into material with an average porosity of 25-50 mu m was proved."
For more information on this research see: Production, characterisation, and cytocompatibility of porous titanium-based particulate scaffolds. Journal of Materials Science-Materials in Medicine, 2013;24(10):2337-2358. Journal of Materials Science-Materials in Medicine can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands (see also Bone Research).
Our news correspondents report that additional information may be obtained by contacting B.J.C. Luthringer, HZG, Inst Mat Res, Geesthacht, Germany. Additional authors for this research include F. Ali, H. Akaichi, F. Feyerabend, T. Ebel and R. Willumeit.
Keywords for this news article include: Europe, Germany, Titanium, Geesthacht, Light Metals, Bone Research
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