By a News Reporter-Staff News Editor at Health & Medicine Week -- Research findings on Bacterial Infections are discussed in a new report. According to news reporting originating from Clermont Ferrand, France, by NewsRx correspondents, research stated, "The development of devices with surfaces that have an effect against microbial adhesion or viability is a promising approach to the prevention of device-related infections. To review the strategies used to design devices with surfaces able to limit microbial adhesion and/or growth."
Our news editors obtained a quote from the research from University Hospital, "A PubMed search of the published literature. One strategy is to design medical devices with a biocidal agent. Biocides can be incorporated into the materials or coated or covalently bonded, resulting either in release of the biocide or in contact killing without release of the biocide. The use of biocides in medical devices is debated because of the risk of bacterial resistance and potential toxicity. Another strategy is to modify the chemical or physical surface properties of the materials to prevent microbial adhesion, a complex phenomenon that also depends directly on microbial biological structure and the environment. Anti-adhesive chemical surface modifications mostly target the hydrophobicity features of the materials. Topographical modifications are focused on roughness and nanostructures, whose size and spatial organization are controlled. The most effective physical parameters to reduce bacterial adhesion remain to be determined and could depend on shape and other bacterial characteristics. A prevention strategy based on reducing microbial attachment rather than on releasing a biocide is promising. Evidence of the clinical efficacy of these surface-modified devices is lacking."
According to the news editors, the research concluded: "Additional studies are needed to determine which physical features have the greatest potential for reducing adhesion and to assess the usefulness of antimicrobial coatings other than antibiotics."
For more information on this research see: Modification of the surfaces of medical devices to prevent microbial adhesion and biofilm formation. Journal of Hospital Infection, 2013;85(2):87-93. Journal of Hospital Infection can be contacted at: W B Saunders Co Ltd, 32 Jamestown Rd, London NW1 7BY, England. (Elsevier - www.elsevier.com; Journal of Hospital Infection - www.elsevier.com/wps/product/cws_home/623052)
The news editors report that additional information may be obtained by contacting C. Desrousseaux, CHU Clermont Ferrand, Serv Hyg Hosp, Clermont Ferrand, France. Additional authors for this research include V. Sautou, S. Descamps and O. Traore (see also Bacterial Infections).
Keywords for this news article include: France, Europe, Clermont Ferrand, Bacterial Infections and Mycoses
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