By a News Reporter-Staff News Editor at Health & Medicine Week -- Research findings on Biological and Medical Science are discussed in a new report. According to news originating from Ashburn, Virginia, by NewsRx editors, the research stated, "The zebrafish Danio rerio has emerged as a powerful vertebrate model system that lends itself particularly well to quantitative investigations with live imaging approaches, owing to its exceptionally high optical clarity in embryonic and larval stages. Recent advances in light microscopy technology enable comprehensive analyses of cellular dynamics during zebrafish embryonic development, systematic mapping of gene expression dynamics, quantitative reconstruction of mutant phenotypes and the system-level biophysical study of morphogenesis."
Our news journalists obtained a quote from the research from Howard Hughes Medical Institute, "Despite these technical breakthroughs, it remains challenging to design and implement experiments for in vivo long-term imaging at high spatio-temporal resolution. This article discusses the fundamental challenges in zebrafish long-term live imaging, provides experimental protocols and highlights key properties and capabilities of advanced fluorescence microscopes. The article focuses in particular on experimental assays based on light sheet-based fluorescence microscopy, an emerging imaging technology that achieves exceptionally high imaging speeds and excellent signal-to-noise ratios, while minimizing light-induced damage to the specimen."
According to the news editors, the research concluded: "This unique combination of capabilities makes light sheet microscopy an indispensable tool for the in vivo long-term imaging of large developing organisms."
For more information on this research see: In vivo imaging of zebrafish embryogenesis. Methods, 2013;62(3):268-278. Methods can be contacted at: Academic Press Inc Elsevier Science, 525 B St, Ste 1900, San Diego, CA 92101-4495, USA. (Elsevier - www.elsevier.com; Methods - www.elsevier.com/wps/product/cws_home/622914)
The news correspondents report that additional information may be obtained from P.J. Keller, Howard Hughes Med Inst, Ashburn, VA 20147, United States (see also Biological and Medical Science).
Keywords for this news article include: Ashburn, Virginia, Technology, United States, North and Central America, Biological and Medical Science
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