By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Gram-Positive Bacteria have been published. According to news reporting from Columbus, Ohio, by NewsRx journalists, research stated, "Use of bacteriocins in food preservation has received great attention in recent years. The goal of this study is to characterize enterocin RM6 from Enterococcus faecalis OSY-RM6 and investigate its efficacy against Listeria monocytogenes in cottage cheese."
The news correspondents obtained a quote from the research from Ohio State University, "Enterocin RM6 was purified from E. faecalis culture supernatant using ion exchange column, multiple C18-silica cartridges, followed by reverse-phase high-performance liquid chromatography. The molecular weight of enterocin RM6 is 7145.0823 as determined by mass spectrometry (MS). Tandem mass spectrometry (MS/MS) analysis revealed that enterocin RM6 is a 70-residue cyclic peptide with a head-to-tail linkage between methionine and tryptophan residues. The peptide sequence of enterocin RM6 was further confirmed by sequencing the structural gene of the peptide. Enterocin RM6 is active against Gram-positive bacteria, including L. monocytogenes, Bacillus cereus, and methicillin-resistant Staphylococcus aureus (MRSA). Enterocin RM6 (final concentration in cottage cheese, 80 AU/mL) caused a 4-log reduction in population of L. monocytogenes inoculated in cottage cheese within 30 min of treatment."
According to the news reporters, the research concluded: "Therefore, enterocin RM6 has potential applications as a potent antimicrobial peptide against foodborne pathogens in food."
For more information on this research see: Characterization and application of enterocin RM6, a bacteriocin from Enterococcus faecalis. Biomed Research International, 2013;2013():206917 (see also Gram-Positive Bacteria).
Our news journalists report that additional information may be obtained by contacting E. Huang, Dept. of Food Science and Technology, The Ohio State University, Columbus, OH 43210, United States. Additional authors for this research include L. Zhang, Y.K. Chung, Z. Zheng and A.E Yousef.
Keywords for this news article include: Ohio, Columbus, Bacteriocins, United States, Enterococcaceae, Bacterial Proteins, Enterococcus faecalis, Gram Positive Bacteria, Gram-Positive Bacteria, North and Central America, Pore Forming Cytotoxic Proteins.
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