By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Proteobacteria. According to news reporting out of Bhavnagar, India, by NewsRx editors, research stated, "Quorum quenching (QQ) is an effective approach for the prevention of bacterial infections involving biofilms. This study reports the QQ and anti-biofilm activities of a rhizospheric bacterium identified as Stenotrophomonas maltophilia BJ01."
Our news journalists obtained a quote from the research from Central Salt and Marine Chemicals Research Institute, "The QQ activity was demonstrated using Chromobacterium violaceum CV026 as a biosensor. A maximum of 95% reduction in violacein production, a quorum sensing-regulated behavior, was observed. Gas chromatography-mass spectroscopy of the extract showed that the active compound was cis-9-octadecenoic acid, which was confirmed by electronspray ionization-mass spectroscopy data. The extract also inhibited biofilm formation of Pseudomonas aeruginosa ATCC 9027 without affecting its growth. Scanning electron and atomic force microscopy showed architectural disruption of the biofilm when treated with the extract. This is the first report of the QQ and anti-biofilm activities of cis-9-octadecenoic acid isolated from any bacterium. It may have the potential to combat detrimental infections with P. aeruginosa."
According to the news editors, the research concluded: "Further validation is required for any possible medical application."
For more information on this research see: Cis-9-octadecenoic acid from the rhizospheric bacterium Stenotrophomonas maltophilia BJ01 shows quorum quenching and anti-biofilm activities. Biofouling, 2013;29(7):855-67 (see also Proteobacteria).
Our news journalists report that additional information may be obtained by contacting V.K. Singh, Discipline of Marine Biotechnology and Ecology, CSIR-Central Salt and Marine Chemicals Research Institute, Bhavnagar, India. Additional authors for this research include K. Kavita, R. Prabhakaran and B. Jha.
Keywords for this news article include: Asia, India, Bhavnagar, Proteobacteria, Xanthomonadaceae, Gram Negative Bacteria, Stenotrophomonas maltophilia, Gram Negative Aerobic Bacteria, Gram Negative Aerobic Rods and Cocci.
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