By a News Reporter-Staff News Editor at Computer Weekly News -- Data detailed on Bone Research have been presented. According to news reporting originating from Bauru, Brazil, by VerticalNews correspondents, research stated, "The main purpose of this study was to determine the accuracy of cone beam CT (CBCT) in measuring the trabecular bone microstructure, in comparison with micro-CT. The subobjective was to examine to what extent bone quality assessment is influenced by X-ray tube current and voltage settings as well as soft tissue surrounding the bone."
Our news editors obtained a quote from the research from the University of Sao Paulo, "Eight human mandibular bone samples were scanned using three different clinical exposure protocol within water (W1-3) and without water (NW1-3) by a high-resolution (80 mu m) CBCT machine (3D Accuitomo 170 ®; Morita, Kyoto, Japan). Subsequently, the samples underwent micro-CT scanning (SkyScan 1174 ®; SkyScan, Antwerp, Belgium). After image acquisition, similar volumes of interest of the trabecular structures captured with CBCT and micro-CT were aligned with each other. Segmentation was then performed, and the morphometric parameters were quantified within the volumes of interest by CTAn software (CTAnalyser ®; SkyScan, Antwerp, Belgium). Descriptive statistical analyses and multiple comparisons between all protocols were applied in R software. High positive Pearson's correlation coefficients were observed between CBCT and micro-CT protocols for all tested morphometric indices except for trabecular thickness. No significant differences were observed between all exposure protocols except for trabecular separation. When examining the soft-tissue effect on trabecular bone structures, no significant differences between NW (1-3) and W (1-3) protocols were observed for all variables. The present study demonstrated the potential of high-resolution CBCT imaging for in vivo applications of quantitative bone morphometry and bone quality assessment."
According to the news editors, the research concluded: "However, the overestimation of morphometric parameters and acquisition settings in CBCT must be taken into account."
For more information on this research see: A comparative evaluation of cone beam CT and micro-CT on trabecular bone structures in the human mandible. Dentomaxillofacial Radiology, 2013;42(8):29-35. Dentomaxillofacial Radiology can be contacted at: British Inst Radiology, 36 Portland Place, London W1N 4AT, England.
The news editors report that additional information may be obtained by contacting J. Van Dessel, University of Sao Paulo, Sch Dental, Dept. of Stomatol, Bauru, Brazil. Additional authors for this research include Y. Huang, M. Depypere, I. Rubira-Bullen, F. Maes and R. Jacobs.
Keywords for this news article include: Bauru, Brazil, Software, South America, Bone Research
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