In a unique
C. diff causes severe diarrhoea, cramps and sometimes life-threatening complications, and has traditionally been thought to be transmitted within hospitals from other sick C.diff patients.
The research found that less than one in five cases of the so called "hospital superbug" were likely to have been caught from other hospital cases of C.diff, where the focus of infection control measures has been.
Researchers also found the total number of cases of C.diff, whether acquired from other sick patients in hospitals or acquired from elsewhere, fell over the three-year period. As a result, the research suggested stringent infection control measures in hospitals were not the most significant factor in curbing the infection.
He said: "This is a landmark study in understanding how patients with C. diff are linked. The results have an important message for infection teams. Continuing on the same path to controlling C.diff will not ensure that all preventable cases are avoided. New measures are needed to prevent this bug spreading and being provoked to cause infection."
The study, supported by the
Prof Peto said that during an overlapping period to the study, the use of antibiotics fell across 175 English hospitals. He added: "C.diff is resistant to antibiotics and that is the key."
"Our study indicates that restricting the use of antibiotics may be more effective in reducing the number people who fall ill with C.diff than lowering transmission rates through infection control measures."
By assessing the genetic variation between C.diff cases, the team identified those cases that were matched and were likely to be linked. By adding hospital records and the community movements of each case, they worked out if that transmission was likely to have happened as a result of hospital or patient contact.
They found that 35 per cent of cases were so genetically similar that they were likely to be caused by direct transmission. Of that group, just over half (55%) could be linked by hospital contact. In total, only 19 per cent of all cases could be clearly linked to hospital transmission from other sick patients with C.diff.
Prof Peto said: "Additionally, 45 per cent of all cases were so different that they could not have come from another sick C.diff patient in
Keywords for this news article include: Hospital, Infection Control, University of
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2013, NewsRx LLC
Most Popular Stories
- 15 Myths That Could Ruin Your Hispanic Ad Campaign
- Bitcoin Clones Lurch Onto Financial Scene
- General Motors Names Mary Barra as First Female CEO
- Clinton to Keynote Annual Simmons Leadership Conference
- AIG to Create 230 Jobs in Charlotte
- How Bitcoin and Other Cryptocurrencies Work
- Californians Want to Legalize Marijuana
- Selena Gomez, Shakira Among Top Hispanic Searches
- Pacific Trade Pact Delay Hinders U.S. Pivot to Asia
- PhD Project Grooms Business Profs