By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Life Science Research. According to news reporting originating in Boston, Massachusetts, by NewsRx journalists, research stated, "To present a novel design of an implantable glaucoma valve based on ferrofluidic nanoparticles and to compare it with a well-established FDA approved valve. Massachusetts Eye & Ear Infirmary, Boston, USA."
The news reporters obtained a quote from the research from the Harvard School of Medicine, "A glaucoma valve was designed using soft lithography techniques utilizing a water-immiscible magnetic fluid (ferrofluid) as a pressure-sensitive barrier to aqueous flow. Two rare earth micro magnets were used to calibrate the opening and closing pressure. In-vitro flow measurements were performed to characterize the valve and to compare it to Ahmedô glaucoma valve. The reliability and predictability of the new valve was verified by pressure/flow measurements over a period of three months and X-ray diffraction (XRD) analysis over a period of eight weeks. In vivo assessment was performed in three rabbits. In the in vitro experiments, the opening and closing pressures of the valve were 10 and 7 mmHg, respectively. The measured flow/pressure response was linearly proportional and reproducible over a period of three months (1.8 l/min at 12 mmHg; 4.3 l/min at 16 mmHg; 7.6 l/min at 21 mmHg). X-ray diffraction analysis did not show oxidization of the ferrofluid when exposed to water or air. Preliminary in vivo results suggest that the valve is biocompatible and can control the intraocular pressure in rabbits. The proposed valve utilizes ferrofluid as passive, tunable constriction element to provide highly predictable opening and closing pressures while maintaining ocular tone. The ferrofluid maintained its magnetic properties in the aqueous environment and provided linear flow to pressure response. Our in-vitro tests showed reliable and reproducible results over a study period of three months."
According to the news reporters, the research concluded: "Preliminary in-vivo results were very promising and currently more thorough investigation of this device is underway."
For more information on this research see: A novel implantable glaucoma valve using ferrofluid. Plos One, 2013;8(6):e67404. (Public Library of Science - www.plos.org; Plos One - www.plosone.org)
Our news correspondents report that additional information may be obtained by contacting E.I. Paschalis, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States. Additional authors for this research include J. Chodosh, R.A. Sperling, B. Salvador-Culla and C. Dohlman (see also Life Science Research).
Keywords for this news article include: Boston, Massachusetts, United States, Life Science Research, North and Central America.
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