By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Enzymes and Coenzymes is the subject of a report. According to news reporting from Troy, New York, by NewsRx journalists, research stated, "Enzyme-based systems represent a user- and environmentally-friendly alternative to current corrosive and/or toxic decontamination technologies used for microbial decontamination. Herein an easily deployable enzyme-nanosupport hybrid system was developed for in situ generation of hypochlorous acid (HOG), a strong decontaminant."
The news correspondents obtained a quote from the research from Rensselaer Polytechnic Institute, "The user-controlled strategy allowed co-immobilization of two different enzymes at a nanosupport interface and decontaminant generation through a chain reaction. For this, glucose oxidase was used as the working enzyme and co-immobilized onto multi-walled carbon nanotubes along with chloroperoxidase. Our hypothesis was that hydrogen peroxide produced at the nanosupport interface through the glucose oxidase enzymatic reaction can further be used as substrate by the co-immobilized CPO to convert (Cl-) into HOC. The chemistry of the immobilization method, as well as the enzyme loading, activity, kinetics and enzyme stability at the nanointerface were evaluated. The multi-enzyme system was found to be able to initiate and propagate the chain reaction resulting in decontaminant production."
According to the news reporters, the research concluded: "The strong capability of HOCl generation can be viewed as an important first step toward creating self-sustainable microbial decontamination coatings to be used against various pathogens such as bacteria and spores."
For more information on this research see: BioNano engineered hybrids for hypochlorous acid generation. Process Biochemistry, 2013;48(9):1355-1360. Process Biochemistry can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Process Biochemistry - www.elsevier.com/wps/product/cws_home/422857)
Our news journalists report that additional information may be obtained by contacting A.S. Campbell, Rensselaer Polytechnic Inst, Dept. of Chem & Biol Engn, Troy, NY 12180, United States. Additional authors for this research include C.B. Dong, J.S. Dordick and C.Z. Dinu (see also Enzymes and Coenzymes).
Keywords for this news article include: Troy, New York, Chemicals, Chemistry, Engineering, United States, Hypochlorous Acid, Enzymes and Coenzymes, North and Central America
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