By a News Reporter-Staff News Editor at Health & Medicine Week -- Research findings on Fibroblasts are discussed in a new report. According to news reporting out of Portici, Italy, by NewsRx editors, research stated, "The aim of this study was to analyze the features of an oxidized titanium implant surface and to evaluate its effects on the response of human gingival fibroblasts. 10 mm x 10 mm x 1 mm turned (control) and oxidized (test) titanium samples (P.H.I. s.r.l., Italy) were examined by scanning electron microscopy and atomic force microscopy and characterized by height, spatial and hybrid roughness parameters."
Our news journalists obtained a quote from the research from National Research Council, "Primary cultures of human gingival fibroblasts were seeded on titanium samples, and cell morphology, adhesion, proliferation and extracellular matrix deposition, in terms of type I collagen synthesis, were evaluated. Control and test surfaces appeared considerably different at the microscopic analyses: turned samples were grooved, whereas oxidized surfaces showed a more complex micro- and nano-scaled texture, as evidenced by roughness parameters. Cell adhesion and proliferation rate, as well as collagen synthesis, were greater on oxidized vs turned surfaces. Although both control and test samples were in the range of average roughness proper of smooth surfaces, they exhibited significantly different topographic properties in terms of height and, mostly, hybrid parameters."
According to the news editors, the research concluded: "Furthermore, oxidized surfaces enhanced human gingival fibroblast adhesion, proliferation and extracellular matrix deposition, and this could be due to the different structure at micro-and nano-scale levels."
For more information on this research see: Human gingival fibroblast functions are stimulated by oxidized nano-structured titanium surfaces. Journal of Dentistry, 2013;41(10):900-907. Journal of Dentistry can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Journal of Dentistry - www.elsevier.com/wps/product/cws_home/30441)
Our news journalists report that additional information may be obtained by contacting L. Guida, Natl Res Council IMCB CNR, Inst Composite & Biomed Mat, I-80055 Portici, Italy. Additional authors for this research include A. Oliva, M.A. Basile, M. Giordano, L. Nastri and M. Annunziata (see also Fibroblasts).
Keywords for this news article include: Italy, Europe, Portici, Titanium, Fibroblasts, Light Metals, Connective Tissue Cells
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