By a News Reporter-Staff News Editor at Journal of Technology -- A new study on X-Ray Technology is now available. According to news originating from Winston Salem, North Carolina, by VerticalNews correspondents, research stated, "The purpose of this study was to distinguish passive retention of microbubbles in liver sinusoids from active intracellular retaining, and to provide further evidence of post vascular liver specific phase of perflubutane microbubble contrast-enhanced ultrasound for potential use in the detection of focal liver lesions. Fifty-four rats were divided into three groups: saline group (G1, as a control, n = 6), sulphur hexafluoride microbubble group (G2, n = 24) and perflubutane microbubble group (G3, n = 24)."
Our news journalists obtained a quote from the research from Wake Forest University, "The livers were perfused at 2, 5, 10 and 20 min after injection of perflubutane or sulphur hexafluoride gas-filled microbubbles or normal saline. Changes in contrast-enhanced images within the liver were quantified. After perfusion, the echogenicity of the liver in the saline group increased from -49.44 +/- 0.08 dB to -44.37 +/- 1.02 dB (p < 0.05). In G2, the enhancement decreased significantly after perfusion at 2 and 5 min, and increased at 10 and 20 min (all p< 0.05). In G3, the enhancement decreased from -18.05 +/- 2.28 dB to -26.76 +/- 1.69 dB only at 2 min after perfusion (p < 0.05). Perflubutane microbubbles provided a post vascular liver specific phase on contrast-enhanced ultrasound, which could begin as early as 5 min after administration of the contrast agent in rats."
According to the news editors, the research concluded: "This study suggests that perflubutane microbubbles could result in a liver specific phase and provide valuable information for diagnosis and detection of focal liver lesions which may improve the efficiency of contrast-enhanced ultrasound in clinical diagnoses of liver diseases."
For more information on this research see: Liver specific phase of perflubutane microbubbles contrast-enhanced ultrasound for potential use in the diagnosis of focal liver lesions. Journal of X-Ray Science and Technology, 2013;21(3):409-418. Journal of X-Ray Science and Technology can be contacted at: Ios Press, Nieuwe Hemweg 6B, 1013 Bg Amsterdam, Netherlands.
The news correspondents report that additional information may be obtained from Q. Ji, Wake Forest University, Wake Forest Inst Regenerat Med, Winston Salem, NC 27109, United States. Additional authors for this research include G.H. Liu, X.Z. Sun, G.J. Liu, M.D. Lu, X.Y. Xie, M. Xu, Y.Y. Zhang and S.G. Zheng.
Keywords for this news article include: Winston Salem, United States, North Carolina, X-Ray Technology, North and Central America
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