By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Polyethylene Glycols. According to news reporting originating from Shanghai, People's Republic of China, by NewsRx correspondents, research stated, "Novel nanocomposite hydrogels composed of hyaluronan (HA), poly(vinyl alcohol) (PVA) and silver nanoparticles were prepared by several cycles of freezing and thawing. The nanocomposite was then characterised using Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), wide-angle X-ray diffraction (XRD) and scanning electron microscopy (SEM)."
Our news editors obtained a quote from the research from Shanghai Jiao-Tong University, "The complex hydrogels consisted of semi-interpenetrating network structures, with PVA microcrystallines as junction zones. By increasing the HA content, the crystallinity and melting temperature of the complex hydrogels decreased, whereas the glass transition temperatures of these materials increased because of the steric hindrance of HA and the occurrence of intermolecular interactions through hydrogen bonding between HA and PVA in the complex hydrogels. Swelling studies showed that in comparison with the swelling properties of the cryogels from PVA alone, those of the complex hydrogels can be significantly improved and presented in a pH-sensitive manner. In addition, silver nanoparticles were synthesised through UV-initiated photoreduction with HA functioning as a reducing agent and stabiliser. The silver nanoparticles were then incorporated in situ into the HA/PVA complex hydrogel matrix. The size and morphology of the as-prepared Ag nanoparticles were investigated through ultraviolet-visible light spectroscopy, transmission electron microscopy, XRD and thermogravimetric analysis. The experimental results indicated that silver nanoparticles 20-50 nm in size were uniformly dispersed in the hydrogel matrix. The antibacterial effects of the HA/PVA/Ag nanocomposite hydrogel against Escherichia coli were evaluated."
According to the news editors, the research concluded: "The results show that this nanocomposite hydrogel possesses high antibacterial property and has a potential application as a wound dressing material."
For more information on this research see: Development of a complex hydrogel of hyaluronan and PVA embedded with silver nanoparticles and its facile studies on Escherichia coli. Journal of Biomaterials Science Polymer Edition, 2013;24(12):1410-25 (see also Polyethylene Glycols).
The news editors report that additional information may be obtained by contacting F. Zhang, Dept. of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, People's Taiwan. Additional authors for this research include J. Wu, D. Kang and H. Zhang.
Keywords for this news article include: Asia, Shanghai, Alcohols, Hydrogel, Nanoparticle, Nanotechnology, Escherichia coli, Organic Chemicals, Enterobacteriaceae, Polyethylene Glycols, Emerging Technologies, Gram Negative Bacteria, People's Republic of China.
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