By a News Reporter-Staff News Editor at Clinical Oncology Week -- New research on Oncology is the subject of a report. According to news reporting originating in Kochi, Japan, by NewsRx journalists, research stated, "To distinguish acinar cell carcinoma (ACC) from pancreatic adenocarcinoma (AC) by comparing their computed tomography findings. Patients with ACC and AC were identified on the basis of results obtained using surgically resected pancreatectomy specimens."
The news reporters obtained a quote from the research from Health Science Center, "The preoperative computer tomographic images of 6 acinar cell carcinoma patients and 67 pancreatic adenocarcinoma patients in 4 phases (non-contrast, arterial, portal venous, and delayed phase) were compared. The scan delay times were 40, 70, and 120 s for each contrast-enhanced phase. The visual pattern, tomographic attenuation value, and time attenuation curve were assessed and compared between AC and ACC cases using the chi(2) test, Wilcoxon signed-rank test, and Mann Whitney U test. The adenocarcinomas tended to be hypodense in all 4 phases. The acinar cell carcinomas also tended to be hypodense in the 3 contrast-enhanced phases, although their computed tomographic attenuation values were higher. Further, 5 of the 6 acinar cell carcinomas (83%) were isodense in the non-contrast phase. The time attenuation curve of the adenocarcinomas showed a gradual increase through the 4 phases, and all adenocarcinomas showed peak enhancement during the delayed phase. The time attenuation curve of the acinar cell carcinomas showed peak enhancement during the portal venous phase in 4 cases and during the arterial phase in 2 cases. None of the 6 acinar cell carcinomas showed peak enhancement during the delayed phase."
According to the news reporters, the research concluded: "The tumor density in the non-contrast phase and time attenuation curve pattern clearly differ between acinar cell carcinomas and adenocarcinomas, and multidetector-row computed tomography can thus distinguish these tumors."
For more information on this research see: Comparison of pancreatic acinar cell carcinoma and adenocarcinoma using multidetector-row computed tomography. World Journal of Gastroenterology, 2013;19(34):5713-5719. World Journal of Gastroenterology can be contacted at: Baishideng Publ Grp Co Ltd, Room 1701, 17-F, Henan Building, No. 90, Jaffe Rd, Wanchai, Hong Kong 100025, Peoples R China. (Baishideng Publishing Group - www.wjgnet.com/; World Journal of Gastroenterology - www.wjgnet.com/1007-9327/current.htm)
Our news correspondents report that additional information may be obtained by contacting T. Sumiyoshi, Kochi Hlth Sci Center, Dept. of Surg Gastroenterol, Kochi 7818555, Japan. Additional authors for this research include Y. Shima, T. Okabayashi, A. Kozuki and T. Nakamura (see also Oncology).
Keywords for this news article include: Asia, Kochi, Japan, Oncology, Pancreas, Adenocarcinomas, Gastroenterology, Acinar Cell Cancer, Imaging Technology, Computed Tomography, Acinar Cell Carcinoma
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