By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Fullerenes have been published. According to news reporting out of Recife, Brazil, by NewsRx editors, research stated, "An immunosensor for the non-structural protein 1 (NS1) of the dengue virus based on carbon nanotube-screen printed electrodes (CNT-SPE) was successfully developed. A homogeneous mixture containing carboxylated carbon nanotubes was dispersed in carbon ink to prepare a screen printed working electrode."
Our news journalists obtained a quote from the research from Federal University, "Anti-NS1 antibodies were covalently linked to CNT-SPE by an ethylenediamine film strategy. Amperometrical responses were generated at -0.5 V vs. Ag/AgCl by hydrogen peroxide reaction with peroxidase (HRP) conjugated to the anti-NS1. An excellent detection limit (in the order of 12 ng mL(-1)) and a sensitivity of 85.59 ?A mM(-1)cm(-2) were achieved permitting dengue diagnostic according to the clinical range required. The matrix effect, as well as the performance of the assays, was successfully evaluated using spiked blood serum sample obtaining excellent recovery values in the results. Carbon nanotubes incorporated to the carbon ink improved the reproducibility and sensitivity of the CNT-SPE immunosensor."
According to the news editors, the research concluded: "This point-of-care approach represents a great potential value for use in epidemic situations and can facilitate the early screening of patients in acute phase of dengue virus."
For more information on this research see: A sensor tip based on carbon nanotube-ink printed electrode for the dengue virus NS1 protein. Biosensors & Bioelectronics, 2013;44():216-21. (Elsevier - www.elsevier.com; Biosensors & Bioelectronics - www.elsevier.com/wps/product/cws_home/405913)
Our news journalists report that additional information may be obtained by contacting A.C. Dias, Biomedical Engineering Laboratory, Federal University of Pernambuco, Campus da Saude, Recife, Brazil. Additional authors for this research include S.L. Gomes-Filho, M.M. Silva and R.F Dutra (see also Fullerenes).
Keywords for this news article include: Recife, Brazil, Viruses, Virology, Fullerenes, South America, Nanotechnology, Carbon Nanotubes, Emerging Technologies.
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