The general public still believes that the big pharmaceutical companies do great research. As a result, the public looks to these companies to save them from cancer, heart disease, Alzheimer’s disease, and many others.
Data shows this hope is misdirected.
As it turns out, the great breakthroughs hailed by the pharmaceutical industry, are not that great. In spite of tremendous scientific, technical and managerial advancements, the big pharmaceutical companies introduce fewer new drugs every year. Moreover, most of these "new" drugs are actually small variations on existing drugs. Consider a study published in March of 2012 on Nature.com. “The number of new drugs approved per billion US dollars spent on R&D by the pharmaceutical industry fell by half roughly every 9 years since 1950 (2). Scientists call this trend the 'The Productivity Crisis in Drug Discovery.' The financial markets also use the term, 'empty pipeline.' ”
Eight years ago, Professor
As the CBCD recently reported, big pharmaceutical companies are starting to respond to investors’ concerns. For instance,
“It seems that at least part of Teva’s reason for downsizing is the fact that ‘its future hinges on finding new revenue to replace what it earns from the branded product Copaxone (1).’ In other words, they have no new drugs to replace Copaxone. Investors are aware of Teva’s empty pipeline. No new drugs. No new investments. With an empty pipeline, it makes financial sense to invest elsewhere.” –
It is troubling that Big Pharma is in the midst of a productivity crisis. However, the Center also sees this crisis as an opportunity, and would like to suggest Computer Intuition, a new drug discovery technology.
What is ‘Computer Intuition’?
‘Computer Intuition’ is a psycholinguistic-based data-mining program that analyzes scientific text and helps scientists discover new therapeutic features of chemical entities.
“In 1996…a prototype of a psycholinguistic-based data-mining program that analyzes scientific text and assigns a rating to all ideas found in the text” was completed (4). “The higher the rating, the more (‘Computer Intuition’) hints at future events (4).”
“The following is a description of one prospective application of Computer Intuition. In 1995, Frederiksen published a paper entitled:
The authors of the study went on to note that the third idea suggested by Computer Intuition was a new technology. “This technology was not mentioned in Frederiksen’s paper. The three ideas were published in 1997. How predictive was the Computer Intuition analysis? In 2006, Almog, Frederiksen, and four colleagues, published a survey of the academic and commercial field of diagnostic imaging in oral implantology. In their paper, they reported an interesting observation. Beginning in 2000, three years after the publication of the Computer Intuition paper, ‘numerous companies from technology-transfer and commercial standpoint have introduced technology platforms that offer planning and guidance systems to facilitate dental implant placement procedures’, the same technology proposed by the third idea three years earlier (4).”
The CBCD invites pharmaceutical executives to contact the Center to learn more about ‘Computer Intuition’ and how this forward thinking technology can help provide higher returns on investment, and be implemented as part of their R&D efforts.
We invite the media to contact us for interviews at: info (at)buy-gene-eden(dot)com or phone 585-250-9999.
The CBCD published the “Purple” book by Dr.
Read the full story at http://www.prweb.com/releases/2013/10/prweb11222203.htm
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